Additional file 4 of Variants associated with Bedaquiline (BDQ) resistance identified in Rv0678 and efflux pump genes in Mycobacterium tuberculosis isolates from BDQ naïve TB patients in Pakistan
The relationship between the total number of non-synonymous SNPs in candidate loci and the MIC values. The size of the circle represents the number of isolates. a) Ethambutol (embB, embA, embA promote
The purpose of this project is to clarify the new resistance mechanism of Mycobacterium tuberculosis to the antituberculosis drug para-aminosalicylic acid (PAS). For this purpose, BCG was cultured in
corresponds to the tree weights of the prespecified trees. Nodes = {WT = wild type, H = isoniazid, R = rifampin, E = ethambutol and S = streptomycin }.
TB seek is a new nanopore sequencing based test designed for simultaneous TB identification and antibiotic resistance genotyping. The TBseek test is based on multiplex PCR, targeting specific genes fo
