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Supplementary Tables 1-4 from Revealing Targeted Therapy for Human Cancer by Gene Module Maps

Figshare2008-01-15 更新2026-04-28 收录

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https://figshare.com/articles/dataset/Supplementary_Tables_1-4_from_Revealing_Targeted_Therapy_for_Human_Cancer_by_Gene_Module_Maps/22373724 数据链接链接失效反馈

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Supplementary Tables 1-4 from Revealing Targeted Therapy for Human Cancer by Gene Module Maps

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2008-01-15

癌症靶向治疗

RAS信号通路抑制

Crystal structure of BRAF/MEK1 complex with NST-628 and an active RAF dimer Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Dual specificity mitogen-activated protein kinase kina

Protein Data Bank Japan2024-07-10 更新60

First-line targ veted therapies of advanced hepatocellular carcinoma: A Bayesian network analysis of randomized controlled trials

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药物疗效比较

Purpose A variety of targeted drug were developed and proved effective and safe in clinical trials. Our study aims to compare the efficacies and safety of different targeted drugs in advanced hepatoce

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Table S2 from Disruption of TFIIH activities generates a stress gene expression response and reveals possible new targets against cancer

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转录抑制响应

Disruption of the enzymatic activities of the transcription factor TFIIH by the small molecules Triptolide (TPL) or THZ1 could be used against cancer. Here, we used the MCF10A-ErSrc oncogenesis model

Figshare2020-06-01 更新30

Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system. Depletion of Nrf2 in pancreatic cancer cells shifts arginine metabolism into the phosphocreatine energy system

癌细胞重编程

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Depletion of Nrf2 leads to an increase in cellular ROS, reduced glutathione and thiols, and profound reprogramming of metabolism. Unbiased transcriptome analyses show that key enzymes of glycolysis, p

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Crystal structure of PRMT5:MEP50 in complex with MTA and TNG462

蛋白质晶体

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Crystal structure of PRMT5:MEP50 in complex with MTA and TNG462 Descriptor: 1,2-ETHANEDIOL, 5'-DEOXY-5'-METHYLTHIOADENOSINE, CHLORIDE ION, ... Authors: Whittington, D.A. Deposit date: 2025-01-31 Relea

Protein Data Bank Japan2025-03-19 更新30

Supplementary Tables 1-4 from Revealing Targeted Therapy for Human Cancer by Gene Module Maps

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