m6AVar

We collected millions of variants from dbSNP and TCGA project, as well as thousands of m6A sites from 7 miCLIP experiments, 2 PA-m6A-Seq experiments and 244 MeRIP-Seq experiments, together with a large number of predicted m6A sites are involved. At present, m6AVar contains 414,241 m6A-associated variants, which are composed of 352,014 m6A-associated germline mutations from dbSNP and 62,227 m6A-associated somatic mutations from TCGA.我们从单核苷酸多态性数据库（dbSNP）与癌症基因组图谱（TCGA）项目中收集了数百万个变异位点，同时从7项miCLIP实验、2项PA-m6A-Seq实验及244项MeRIP-Seq实验中获取了数千个N6-甲基腺嘌呤（m6A）位点，并纳入了大量预测获得的m6A位点。当前，m6AVar数据集共包含414,241个与m6A相关的变异位点，其中涵盖来自dbSNP的352,014个m6A相关生殖系突变，以及来自TCGA的62,227个m6A相关体细胞突变。

搜集汇总

背景与挑战

背景概述

m6AVar数据集整合了来自dbSNP和TCGA项目，以及多个miCLIP、PA-m6A-Seq和MeRIP-Seq实验的变异和m6A位点信息。它目前包含414,241个m6A相关变异，其中352,014个为dbSNP的种系突变，62,227个为TCGA的体细胞突变。