Genome-wide Profiling of Adenine Base Editor Specificity by EndoV-seq--Target site deep sequencing
收藏NIAID Data Ecosystem2026-05-26 收录
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资源简介：
EndoV-seq utilizes Endonuclease V (EndoV) to nick the inosine (I)-containing DNA strand of genomic DNA that has been deaminated by ABE in vitro. The treated DNA is then whole-genome sequenced to identify overlapping ends generated by EndoV and Cas9 nickase (nCas9). Genomic sites are scored based on DNA reads with overlapping ends to identify both on-target sites and off-target sites.
创建时间：
2019-02-01
