The exoCasMINI exhibits similar specificity for gene editing. Compared to SpCas9, exoCasMINI also exhibited higher specificity for genomic DNA cleavage at the tested sites. We evaluated the specificit

NIAID Data Ecosystem50

Suppression of unwanted CRISPR/Cas9 editing by co-administration of catalytically inactive truncated guide RNAs. Homo sapiens

CRISPR脱靶效应控制

基因编辑特异性

The goal of this study is to develop a novel method for reducing unwanted genomic editing by CRISPR/Cas9 and improve specificity in a variety of cellular contexts.

NIAID Data Ecosystem60

Genome-wide Profiling of Adenine Base Editor Specificity by EndoV-seq. Homo sapiens

碱基编辑器脱靶检测

基因编辑特异性

EndoV-seq utilizes Endonuclease V (EndoV) to nick the inosine (I)-containing DNA strand of genomic DNA that has been deaminated by ABE in vitro. The treated DNA is then whole-genome sequenced to ident

NIAID Data Ecosystem50

Genome-wide specificity of dCpf1 cytidine base editors. Homo sapiens

资源简介：

相关数据集