p values in boldface are significant aX = any HLA-DQB1 allele different from *02 or *0302 bOR = Odds Ratio; 95%CI = 95% Confidence Intervals. Odds Ratios were calculated by binary logistic regression
The ability to predict individual genetic susceptibility to a complex trait disease is a major challenge in modern medicine. One approach to addressing this challenge utilizes an additive combination
ref.: reference group. aMultivariate OR values were adjusted for age, gender, educational level, and cumulative cigarette smoking. *p<0.05 by trend test.
Ref: used as reference values. ORC: Crude Odds Ratio; ORa: Odds Ratio adjusted by logic regression based on age, gender, smoking, and drinking status; 95% CI: 95% confidence interval.Haplotype and gen