One-pot synthesis of bis (phenylimino dihydro thiazolyl-2<i>H</i>-chromene) derivatives

A novel series of bis (phenylimino dihydro thiazolyl-2<i>H</i>-chromene) derivatives have been synthesized through an efficient one-pot multicomponent approach involving different substituted of 3-(2-bromoacetyl)-2<i>H</i>-chromen-2-ones, phenyl isothiocyanates and <i>para</i>-phenylenediamine in presence of dimethylformamide solvent. The target compounds were obtained in a shorter reaction time through simple reaction work up with good yields. All the synthesized products were characterized by their spectral and analytical data like IR, ¹H NMR, ¹³C NMR, Roesy, and mass spectral data.本研究通过高效的一锅多组分合成法，以不同取代的3-(2-溴乙酰基)-2H-色烯-2-酮、异硫氰酸苯酯与对苯二胺为原料，在N,N-二甲基甲酰胺（dimethylformamide）溶剂中反应，合成了一系列新型双(苯亚氨基二氢噻唑基-2H-色烯)衍生物。目标化合物可通过简便的后处理操作，以较短的反应时间获得良好收率。所有合成产物均通过红外光谱（IR）、氢核磁共振谱（¹H NMR）、碳核磁共振谱（¹³C NMR）、Roesy谱以及质谱数据等谱学与分析数据进行了结构表征。