Darwin Operator Symmetry Atlas (DOSA) v2.1.0
收藏Zenodo2026-01-20 更新2026-05-26 收录
下载链接:
https://zenodo.org/doi/10.5281/zenodo.18312342
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资源简介:
Darwin Operator Symmetry Atlas (DOSA) - A comprehensive database of operator-defined symmetries in bacterial replicons.
This dataset contains 24,090,832 window-level symmetry measurements across 959 bacterial genomes, analyzing circular sequence symmetries under the dihedral group Dn (rotations + reverse-complement reflection).
Key Statistics
Total Windows: 24,090,832 records (1.4 GB)
Unique Replicons: 959 bacterial genomes
Window Sizes: 100bp (18.5M), 500bp (3.7M), 1000bp (1.85M)
Quality Validation: 13/13 checks passed (100.0%)
Mean orbit_ratio: 0.99999871 (near-perfect asymmetry)
Palindromes: 3 / 24M windows (0.00001%)
Biological Insights
99.9998% of windows have orbit_ratio ≥ 0.95
Only 37 windows show significant symmetry
Bacterial genomes are informationally complex, not periodic
Files Included
atlas_windows_exact.csv (1.4 GB) - 24M window-level symmetry measurements
atlas_replicons.csv (16 MB) - 114K replicon metadata records
atlas_knowledge.jsonl (627 MB) - 1.1M epistemic knowledge records
Statistics: overall_stats.json, by_window_size.csv, orbit_ratio_histogram.csv, etc.
Documentation: README.md, QUALITY_REPORT.md, STATISTICS_REPORT.md
Reproducibility
Fully reproducible with:
✓ Deterministic outputs (no random seeds)
✓ SHA256 checksums for all genome downloads
✓ Complete audit trail in git history
✓ Source code: https://github.com/agourakis82/darwin-atlas
Mathematical Framework
Dihedral Group Dn: Symmetry of circular sequences under rotations + RC reflection
orbit_size ∈ [1, 2n] where orbit_size divides 2n (Lagrange's theorem)
orbit_ratio = orbit_size / (2n) ∈ [1/(2n), 1.0]
Generic sequences: orbit_ratio ≈ 1.0 (full orbit, maximal asymmetry)
See README.md for complete documentation.
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Zenodo创建时间:
2026-01-20



