Darwin Operator Symmetry Atlas (DOSA) v2.1.1
收藏Zenodo2026-01-20 更新2026-05-26 收录
下载链接:
https://zenodo.org/doi/10.5281/zenodo.18316003
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资源简介:
Darwin Operator Symmetry Atlas (DOSA) - A comprehensive database of operator-defined symmetries in bacterial replicons.
This dataset contains 24,090,832 window-level symmetry measurements across 959 bacterial genomes, analyzing circular sequence symmetries under the dihedral group Dn (rotations + reverse-complement reflection).
Key Statistics
Total Windows: 24,090,832 records (1.4 GB)
Unique Replicons: 959 bacterial genomes
Window Sizes: 100bp (18.5M), 500bp (3.7M), 1000bp (1.85M)
Quality Validation: 13/13 checks passed (100.0%)
Mean orbit_ratio: 0.99999871 (near-perfect asymmetry)
Palindromes: 3 / 24M windows (0.00001%)
Biological Insights
99.9998% of windows have orbit_ratio ≥ 0.95
Only 37 windows show significant symmetry
Bacterial genomes are informationally complex, not periodic
Files Included
atlas_windows_exact.csv (1.4 GB) - 24M window-level symmetry measurements
atlas_replicons.csv (16 MB) - 114K replicon metadata records
atlas_knowledge.jsonl (627 MB) - 1.1M epistemic knowledge records
Statistics: overall_stats.json, by_window_size.csv, orbit_ratio_histogram.csv, etc.
Documentation: README.md, QUALITY_REPORT.md, STATISTICS_REPORT.md
Reproducibility
Fully reproducible with:
✓ Deterministic outputs (no random seeds)
✓ SHA256 checksums for all genome downloads
✓ Complete audit trail in git history
✓ Source code: https://github.com/agourakis82/darwin-atlas
Mathematical Framework
Dihedral Group Dn: Symmetry of circular sequences under rotations + RC reflection
orbit_size ∈ [1, 2n] where orbit_size divides 2n (Lagrange's theorem)
orbit_ratio = orbit_size / (2n) ∈ [1/(2n), 1.0]
Generic sequences: orbit_ratio ≈ 1.0 (full orbit, maximal asymmetry)
See README.md for complete documentation.
达尔文算子对称图谱(Darwin Operator Symmetry Atlas, DOSA)—— 一套收录细菌复制子算子定义对称性的综合数据库。
本数据集涵盖959个细菌基因组的24090832条窗口级对称性测量数据,针对二面体群Dn(旋转与反向互补翻转操作)下的环状序列对称性展开分析。
核心统计指标
总窗口数:24090832条记录(1.4 GB)
唯一复制子:959个细菌基因组
窗口尺寸:100bp(18.5M)、500bp(3.7M)、1000bp(1.85M)
质量验证:13项检查全部通过(通过率100.0%)
平均轨道比率(orbit_ratio):0.99999871(近乎完美的非对称性)
回文序列:2400万条窗口中仅3条(占比0.00001%)
生物学洞察
99.9998%的窗口轨道比率≥0.95
仅37个窗口呈现显著对称性
细菌基因组具备信息复杂性,而非周期性结构
包含文件
atlas_windows_exact.csv(1.4 GB):2400万条窗口级对称性测量数据
atlas_replicons.csv(16 MB):11.4万条复制子元数据记录
atlas_knowledge.jsonl(627 MB):110万条认知知识记录
统计配套文件:overall_stats.json、by_window_size.csv、orbit_ratio_histogram.csv等
文档说明:README.md、QUALITY_REPORT.md、STATISTICS_REPORT.md
可复现性
本数据集可完全复现,支持条件如下:
✓ 确定性输出(无需随机种子)
✓ 所有基因组下载文件均附带SHA256校验和
✓ 完整的Git历史审计轨迹
✓ 源代码地址:https://github.com/agourakis82/darwin-atlas
数学框架
二面体群Dn:环状序列在旋转与反向互补翻转操作下的对称性群
轨道大小(orbit_size)∈[1, 2n],且轨道大小可整除2n(拉格朗日定理)
轨道比率(orbit_ratio)= orbit_size / (2n) ∈[1/(2n), 1.0]
通用序列的轨道比率≈1.0(完整轨道,非对称性最大化)
完整文档请参见README.md。
提供机构:
Zenodo创建时间:
2026-01-20



