In vivo CRISPR screens for Toxoplasma using endomembrane-nucleus sublibrary in WT and Ifngr1-deficient mice
收藏NIAID Data Ecosystem2026-05-01 收录
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资源简介：
We performed in vivo CRISPR screen of Toxoplasma targeting endomembrane and nucleus-related genes to identify in vivo fitness genes in WT and Ifngr1-deficient mice. This sublibrary targeting 395 genes which consisted 3945 gRNAs targeting endomembrane and nucleus-related genes together with dispensable and essential control genes. We performed in vivo CRISPR screens to identify novel virulence factors of Toxoplasma.
创建时间：
2023-06-15
